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ImmunoPrecise and Harbour Antibodies Announce Technology Co-Offering Agreement for Next-Generation Fully-Human Antibody Discovery

 

 

 

 

 

IMMUNOPRECISE ANTIBODIES LTD. (TSX-V: IPA) (OTC PINK: IPATF) ImmunoPrecise Antibodies and Harbour Antibodies, a wholly owned subsidiary of Harbour BioMed, announced today that they have entered into an agreement to combine ImmunoPrecise’s antibody discovery services with Harbour’s H2L2, fully human transgenic mouse platform (Harbour Mice™), offering an industry-leading discovery solution to enable the generation of diverse panels of fully-human therapeutic antibodies. The combined offering eliminates the need for antibody humanization through the use of Harbour Mice™, and benefits from ImmunoPrecise’s full suite of antibody discovery capabilities, spanning antigen design and immunization through discovery, characterization, and lead selection. ImmunoPrecise was selected as a designated CRO to provide its full-service antibody discovery services under the Co-Offering Agreement utilizing the Harbour Mice™.

 

 

“Harbour’s patented H2L2, fully human transgenic mouse platform has been used globally in many multinational pharma, biotech, non-profit organization and academia, and we are pleased to partner with ImmunoPrecise to facilitate easy access to H2L2 Harbour Mice™ and accelerate therapeutic antibody discovery in organizations that have not yet utilized our technology platform”, said Dr. Jingsong Wang, CEO of Harbour BioMed.

 

 

ImmunoPrecise is a full-service discovery antibody CRO that provides a globally-operating, comprehensive platform of therapeutic discovery offerings from target selection, on-site animal access, Rapid Prime Immunization, advanced hybridoma discovery, B-cell screening and sorting, antibody characterization, as well as in vitro and in vivo analyses. ImmunoPrecise’s innovative technologies will allow for antibody screening from Harbour’s H2L2 transgenic mouse platform and are aimed at providing increased antibody diversity within the mouse repertoire, as well as faster, deeper antibody screening compared to traditional technologies alone.

 

 

Harbour’s patented H2L2 fully human transgenic mouse platform provides antibody generation through a normal and natural process in vivo, allowing the powerful platform to generate affinity matured, fully human and highly diversified antibody repertoire with excellent solubility and developability. Over the past few years, the Harbour Mice™ have emerged as industry leading with over 40 licensees including multinational pharma, biotech, non-profit organizations and academia.

 

 

Dr. Jennifer Bath, CEO and President of Immunoprecise commented: “Immunoprecise is happy to partner with Harbour Antibodies in a combined effort to bring global and innovative offerings to today’s researchers, with the common goal of aiding clients in developing successful, therapeutic antibodies for the patients of tomorrow.”

 

 

About Harbour Antibodies BV

 

 

Harbour Antibodies is a fully owned subsidiary of Harbour BioMed, a global biopharmaceutical company discovering and developing innovative therapeutics for oncology and immunological diseases (www.harbourbiomed.com). Harbour Antibodies owns two strains of transgenic mice (Harbour Mice™) for generating human therapeutic antibodies: (1) H2L2 – mice that generate antibodies comprised of two heavy chains and two light chains with fully human variable regions; and (2) HCAb – mice that generate novel “heavy chain only” antibodies. The HCAb mice enable the development of antibody fragment-based therapeutics such as nanobodies, bi-specific antibodies and CAR-T with favorable drug-like properties. For additional information, please visit http://harbourantibodies.com

 

 

About ImmunoPrecise Antibodies Ltd.

 

 

ImmunoPrecise is a full-service, therapeutic antibody discovery company focused on the next generation of antibody discovery, to deliver the most therapeutically-relevant antibodies, in a shorter period of time, with the highest probability of succeeding to clinical trials.

 

 

ImmunoPrecise operates from state-of-the-art laboratory facilities located at the Vancouver Island Technology Park in Victoria, British Columbia, in collaboration with its wholly-owned subsidiary operations at U-Protein Express B.V., in the Life Science Incubator, Utrecht, and ModiQuest Research, Oss, both in the Netherlands.

 

 

The services offered to clients include antibody discovery in wild-type and transgenic mouse and rat models, custom phage display libraries, and rabbit monoclonal antibodies, all against a broad spectrum of antigens. The Company also offers B-cell screening and sorting services that may decrease discovery timelines and enhance the probability of finding a therapeutic antibody of interest. In addition, the Company provides a broad range of additional services related to its biotherapeutic discovery platforms including immunologically-based assays, recombinant protein manufacturing, humanization, optimization, phage display, stable cell line development, and advanced solutions to challenges faced by clients in antibody-related research and development.  Cryopreservation services are provided for the storage of valuable biological materials including hybridoma clones, plasmid constructs, and cell lines. The antibodies produced by ImmunoPrecise target a wide variety of therapeutic, diagnostic and research applications.

 

Posted August 30, 2018

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