GB Sciences, Inc. (OTCQB: GBLX) has completed the technology transfer for the manufacturing of time-released nanoparticles containing a cannabinoid-based therapeutic for neuropathic pain from the University of Seville. As announced in Q4 of 2017, GB Sciences has obtained the exclusive worldwide license to the intellectual property covering this time-released cannabinoid formulation from the University of Seville, the Centro de Investigación Biomédica en Red de Salud Mental and the University of Cadiz. These cannabinoid-based nanoparticles have demonstrated sustained relief from neuropathic pain for eleven days following a single oral dose in rodents.

“This product could really be a game-changer for patients who suffer from neuropathic pain. We are eager to begin manufacturing these licensed nanoparticles in the US; thus, continuing the development and commercialization of this important therapeutic option,” explained Dr. Andrea Small-Howard, Chief Science Officer of GB Sciences. “Because cannabinoids are lipid-based and highly-labile, nanotechnology-based delivery methods are particularly useful in improving the bioavailability, stability, and consistency of dosing for these powerful therapeutic molecules—especially for treating chronic conditions like neuropathic pain where patients want to have continuous relief from fewer doses of their medicine.”

During their recent technology transfer trip in Seville, Dr. Small-Howard and Dr. Dominick Monaco of GB Sciences were trained by Dr. Mercedes Fernández Arévalo and Dr. Lucía Martín Banderas of USE on all aspects of cannabinoid-based nanoparticle manufacturing, quality control, and freeze-drying for product stability and ease of transport. In addition, GB Sciences has an on-going research collaboration with this group at USE, and they have reported progress towards creating similar time-released versions of GB Sciences’ proprietary myrcene-based complex mixtures for use in treating chronic pain.

“When we find motivated researchers improving the delivery of cannabis-based medicines, like the I+DNanomed group from USE, we form international research partnerships to create drugs that will likely become first-in-class,” said John Poss, CEO and Chairman of GB Sciences. “So of course, we didn’t just license their existing technology, we also engaged them in our development process to improve the efficacy of our other proprietary formulations.”

About GB Sciences, Inc.

GB Sciences, Inc. is a diverse cannabis company, focused on standardized cultivation and production methods, as well as biopharmaceutical research and development. The Company’s goal is creating safe, standardized, pharmaceutical-grade, cannabinoid therapies that target a variety of medical conditions. To learn more about GB Sciences, Inc., go to: http://gbsciences.com.

About University of Seville

The University of Seville (USE—Universidad de Sevilla) is an institution with more than five centuries of history, with an accredited academic tradition, and with recognition as an International Campus of Excellence. All of our qualifications are adapted to the European Higher Education Area and cover all areas of knowledge that provide a public higher education service through study, teaching and research, as well as the generation, development and dissemination of knowledge at the service of Society and Citizenship. USE has made an important effort to improve its research facilities and scientific equipment, which has made it possible to be a Center for Research Excellence that answers public calls for research, engages in collaborations with companies, and creates an important patent portfolio. Our Campus model is integrated in to the city of Sevilla, unfolding in several urban areas and contributing to the vibrancy of the city. www.us.es